2 ml ampoule:
Injection
Generic Name
Nikethamide
Strength
250 mg/ml
Manufacturer
Jayson Pharmaceutical Ltd.
Unit Price
2 ml ampoule: ৳ 12.04 (2 x 5: ৳ 120.40)
🔹 নির্দেশনা
Nikethamide is indicated in-
- Acute respiratory failure
- Respiratory depression following anesthesia
- CNS depression
🔹 ফার্মাকোলজি
Nikethamide also known as nicotinic acid diethylamide is a central & respiratory stimulant. It has direct stimulatory action on CNS, increases the frequency & depth of breathing. It has no immediate impact on the cardiovascular system. It is extensively metabolized in liver. All metabolites & a small amount of unchanged drug is excreted in urine.
🔹 মাত্রা ও ব্যবহারবিধি
2 to 10 mL by slow IV injection of the usual 25% solution every 20 to 30 minutes if necessary. Infants and children are particularly susceptible to toxic effects of nikethamide.
🔹 মিথস্ক্রিয়া
Anesthetic, sympathomimetics, MAOIs, neuromuscular blockers, bupropion.
🔹 প্রতিনির্দেশনা
Porphyria, epilepsy or other convulsive disorders, perebral oedema, airways obstruction, cerebrovascular accident, severe hypertension & ischemic heart diseases.
🔹 পার্শ্ব প্রতিক্রিয়া
Dyspnoea, respiratory problems such as coughing bronchospasm. Other CNS side effects include convulsion, headache & dizziness. Cardiovascular side effects inlude Iteration of blood pressure & cardiac arrhythmia. Over dosage may cause nausea, vomiting & diarrhoea.
🔹 গর্ভাবস্থায় ও স্তন্যদানকালে
There are no enough adequate and controlled studies in pregnant women and nursing mothers.
🔹 সতর্কতা
It should not used in less severe degrees of hypertension or impaired cardiac reverse & hepatic dysfunction.
🔹 সংরক্ষণ
Store below 25°C in a dry place, away from light.
🔍 লোকজন আরও খুঁজছেন
💡 Frequently Asked Questions
Nikethamide is indicated in-
Acute respiratory failure
Respiratory depression following anesthesia
CNS depression
2 to 10 mL by slow IV injection of the usual 25% solution every 20 to 30 minutes if necessary. Infants and children are particularly susceptible to toxic effects of nikethamide.
Dyspnoea, respiratory problems such as coughing bronchospasm. Other CNS side effects include convulsion, headache & dizziness. Cardiovascular side effects inlude Iteration of blood pressure & cardiac arrhythmia. Over dosage may cause nausea, vomiting...
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